Search for:
  • Home/
  • CBD/
  • How Long Does Pepto-Bismol Stay in Your System?

How Long Does Pepto-Bismol Stay in Your System?

Pepto-Bismol is an over-the-counter medicine used to treat digestive symptoms such as nausea, diarrhea, and heartburn.

It also contains bismuth salicylate which reduces inflammation in the lining of the stomach and intestines and kills bacteria that cause stomach problems.

Although Pepto-Bismol is effective in treating constipation, many people wonder how long Pepto-Bismol stays in the body. This article explains how Pepto-Bismol works, its half-life, and how long it takes to clear your body.

How does Pepto-Bismol work?

Pepto-Bismol Bismuth subsalicylate is a mixture of bismuth and salicylic acid. Bismuth subsalicylate coats the stomach and intestines to reduce inflammation and kill ulcer-causing bacteria. The salicylic acid in aspirin reduces pain and fever.

Factors affecting the duration of pepto-bismol in the body

Many factors can affect how long Pepto Bismol stays in your system.

The size of the dose

The duration of action of Pepto-Bismol depends on the dose. The drug takes longer to leave your body. The recommended dose for adults and children 12 years of age and older is 2 tablets or 2 teaspoons every 30 to 60 minutes with up to 8 washes of liquid. It is essential to follow the recommended dosage to avoid side effects.


The expiration date of Pepto Bismol affects how long it stays in your system. Elderly people may take longer to eliminate the drug due to generally reduced kidney and liver function. As your child’s body grows, it may take longer to clear the medicine.

as a picture

Pepto-Bismol affects your health in several ways. People with kidney or liver disease may need more time to clear the drug through the body’s functions. People with gastrointestinal problems may take longer to eliminate the drug due to the slow transit time.


Physiological parameters such as weight and height affect how long Pepto-Bismol stays in the body. People who are overweight may take longer to release the drug than people who are overweight.

Food and drink

Effects of food and drink on how long Pepto-Bismol stays in the body. Eating products containing Pepto-Bismol may decrease the dose. Drinking alcohol increases the effectiveness of the treatment and increases the side effects.

Half-life of Pepto-Bismol

The half-life of a drug is the time it takes to eliminate half of the amount in the body. The half-life of Pepto-Bismol is approximately 12 to 24 hours. This means that half of it is excreted from the body after 12-24 hours.

How long does Pepto-Bismol last in the body?

The effect of Pepto-Bismol usually lasts for 4 to 6 hours. However, it may take 24 to 48 hours for the drug to be eliminated from the body. It is metabolized in the liver and excreted through the kidneys and feces. How long it takes to stop taking the drug depends on the above factors, your age, health, and the dosage.

Pepto-Bismol (bismuth subsalicylate) starts working within 30 minutes to 1 hour to relieve diarrhea, stomach pain, and nausea.

Pepto-Bismol, sometimes called “the pink stuff,” is a safe and effective over-the-counter medication for short-term use. Side effects are usually mild and include darkening of the tongue, darkening of the stool, and constipation. More serious side effects can occur but are rare.

This article explains Pepto-Bismol, how it works, and possible side effects.

The scientific name for the active ingredient in Pepto-Bismol is bismuth subsalicylate.

Bismuth is a mineral with antibacterial, antacid, and antidiarrheal properties.

Subsalicylate is the same class as aspirin.

Active ingredient: Pepto-Bismol;

As the amount of liquid in the intestines increases, the stool becomes more homogeneous.

Reduce inflammation

Avoid intestinal irritation

It reduces the number of pathogens and viruses.

Reduce excess acidity

Pepto can take anywhere from 30 minutes to an hour to make. If you do not feel relief at this stage, do not take a new dose immediately. Follow the dosing instructions on the product packaging.

When to call your doctor

Call your doctor and stop taking Pepto-Bismol immediately.


Diarrhea lasting more than two days

Severe vomiting


Any allergic reaction

In case of an overdose or severe symptoms, call an ambulance immediately.

Why is Pepto stool black?

Before taking Pepto-Bismol

Pepto-Bismol should not be taken for more than 2 days. It is not suitable for people with chronic diarrhea, nasal irritation, or acid breathing.

Consult your doctor before taking


Pepto-Bismol is an oral medication that comes in liquid, tablet, or chewable form. Follow product packaging instructions and directions for use carefully.

Do not use this medicine for more than two days.


Take the liquid Pepto-Bismol using the measuring cup provided. (1 serving equals 1 cup)

If you lose the first aid kit, check the ingredients list. This will determine how much you need.

Initial concentration: 30 milliliters (ml).

Add: 15 ml

Pepto Anti Diarrhea: 10 ml 5

Dispensing medication with a syringe or cup that can be accurately measured. Do not use spoons in the kitchen.

Less than 8 times in 24 hours 5.

Edible capsule

Take two Pepto-Bismol chewable tablets at a time. Do not take more than 16 tablets in 24 hours.

Pepto Kids comes in the form of chewable tablets. Dosage: 6 doses depending on the weight and age of the child.

Up to 24 pounds/up to 2 years: Check with your healthcare professional.

24-27 lbs / 2-5 years: 1 tablet (up to 3 tablets in 24 hours).

48-95 lbs / 6-11 years: 2 pills (up to 6 pills in 24 hours).

If your child’s height and weight do not match the above, please choose the correct size for your child’s weight.

the capsule

Pepto Bismol capsules are available in different formulations. Use only the amount indicated on the label.

Pepto-Bismol LiquiCaps: 2 capsules

Pepto Diarrhea Liquids: 2 capsules

Pepto-Bismol Capsules: 2 capsules

Capsule Pepto Bismol Ultra: 1 capsule

Pepto-Bismol is an over-the-counter medicine used to relieve stomach symptoms such as nausea, diarrhea, and heartburn.

Bismuth sub-salicylic acid, which coats the lining of the stomach and intestines, reduces inflammation and kills the bacteria that cause gastritis.

Despite its effectiveness in relieving stomach symptoms, many people want to know how long Pepto-Bismol stays in their bodies. The body is clear.

How to treat diarrhea?

Pepto-Bismol is commonly used to relieve diarrhea. However, it alleviates common digestive symptoms. Pepto-Bismol is broken down in the body into two different substances: bismuth and salicylic acid. Different parts work differently. To get rid of these symptoms

Bismuth is used as a preservative to relieve diarrhea. Eliminates harmful bacteria that cause gastrointestinal problems. It helps the body absorb more water from the intestines. It lowers the amount of bismuth in the blood and lowers stomach water. So it affects the stomach and intestines.

Salicylic acid is similar to aspirin. Unlike bismuth, this substance is absorbed by the body. Salicylic acid prevents diarrhea and intestinal irritation by inhibiting the enzyme (protein) cyclooxygenase (COX).

By inhibiting COX, salicylic acid reduces intestinal inflammation and slows the movement of food through the stomach. The slow movement of stool in diarrhea helps retain lost nutrients.

as a result

Pepto-Bismol is a powerful medicine used to relieve gastrointestinal symptoms such as nausea, diarrhea, and heartburn. The duration of action and elimination from the body depends on many factors such as dose, age, health status, and body composition. It is important to eat and drink in the recommended amount to avoid adverse reactions. If symptoms persist, see a doctor.

This is a common problem.

Can I take Pepto-Bismol with other medications?

You should check with your doctor before taking Pepto-Bismol with other medications because it may interact with some medications.

Leave A Comment

All fields marked with an asterisk (*) are required